Target

Gene symbol :  
Pla2g6
NCBI gene ID :  
53357
Gene full name :  
Phospholipase A2, group VI
Synonym :  
iPLA₂-VIA, PLA2G6B

Protein function

Protein name :  
PLA2G6
Catalyzes Ca²⁺-independent phospholipid hydrolysis; involved in membrane remodeling

Expected phenotype

Neurodegeneration, locomotor defects

Human disease relevance

Mutations cause neurodegeneration: dystonia-parkinsonism

Model applications

Neurodegeneration and membrane homeostasis models

Keywords:

Phospholipase, Neurodegeneration

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Pla2g6

conditional Knockout mouse

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