Plau conditional Knockout mouse

Target

Gene symbol :

Plau

NCBI gene ID :

18792

Gene full name :

Plasminogen activator, urokinase

Synonym :

Urokinase-type plasminogen activator, UPA

Protein function

Protein name :

PLAU

Converts plasminogen to plasmin, involved in fibrinolysis and tissue remodeling.

Expected phenotype

Impaired wound healing, altered cell migration.

Human disease relevance

Associated with cancer metastasis and thrombotic disorders.

Model applications

Studies on cancer progression and thrombosis.

Keywords:

Fibrinolysis, Cell migration, Cancer

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Plau

conditional Knockout mouse

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