Target

Gene symbol :  
Plekha1
NCBI gene ID :  
101476
Gene full name :  
Pleckstrin homology domain containing A1
Synonym :  
TAPP1

Protein function

Protein name :  
TAPP1 adaptor protein
Binds phosphoinositides and regulates intracellular signaling pathways

Expected phenotype

Altered signaling and cellular trafficking in functional studies

Human disease relevance

Cancer, metabolic disorders

Model applications

Signal transduction and phosphoinositide signaling models

Keywords:

PH domain, lipid signaling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Plekha1

conditional Knockout mouse

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