Plekhg1 conditional Knockout mouse

Target

Gene symbol :

Plekhg1

NCBI gene ID :

213783

Gene full name :

Pleckstrin homology and RhoGEF domain containing G1

Synonym :

PLEKHG1 protein

Protein function

Protein name :

Rho guanine nucleotide exchange factor PLEKHG1

Activates Rho family GTPases, regulating cytoskeleton and cell signaling

Expected phenotype

Altered cytoskeleton dynamics and cell migration

Human disease relevance

Cancer metastasis, vascular disorders

Model applications

Cytoskeleton regulation and signal transduction models

Keywords:

RhoGEF, cytoskeleton

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Plekhg1

conditional Knockout mouse

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