Plekhg3 conditional Knockout mouse

Target

Gene symbol :

Plekhg3

NCBI gene ID :

263406

Gene full name :

Pleckstrin homology and RhoGEF domain containing G3

Synonym :

PLEKHG3 protein

Protein function

Protein name :

Rho guanine nucleotide exchange factor PLEKHG3

Activates Rho family GTPases regulating cytoskeleton organization and cell migration

Expected phenotype

Altered cytoskeleton dynamics and cellular motility

Human disease relevance

Cancer metastasis

Model applications

Cytoskeleton and signal transduction models

Keywords:

RhoGEF, cytoskeleton regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Plekhg3

conditional Knockout mouse

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