Target

Gene symbol :  
Poln
NCBI gene ID :  
272158
Gene full name :  
DNA polymerase nu
Synonym :  
DNA polymerase nu, Pol ν

Protein function

Protein name :  
DNA polymerase nu
Specialized DNA polymerase involved in DNA repair and crosslink repair

Expected phenotype

Increased sensitivity to DNA damage in functional studies

Human disease relevance

Cancer, DNA repair disorders

Model applications

DNA repair and genome stability models

Keywords:

DNA polymerase, DNA repair

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Poln

conditional Knockout mouse

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