Ptch1 conditional Knockout mouse

Target

Gene symbol :

Ptch1

NCBI gene ID :

19206

Gene full name :

Patched 1

Synonym :

Ptc, Patch1

Protein function

Protein name :

Patched 1 receptor

Hedgehog signaling receptor regulating developmental patterning and cell proliferation

Expected phenotype

Developmental defects, tumor susceptibility, embryonic lethality in homozygous knockout

Human disease relevance

Basal cell carcinoma, Gorlin syndrome

Model applications

Developmental biology and cancer models

Keywords:

Hedgehog signaling, receptor

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ptch1

conditional Knockout mouse

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