Target

Gene symbol :  
Pth1r
NCBI gene ID :  
19228
Gene full name :  
Parathyroid hormone 1 receptor
Synonym :  
PTHR, PTH PTHrP receptor

Protein function

Protein name :  
Parathyroid hormone receptor 1
G protein-coupled receptor regulating bone development and calcium homeostasis

Expected phenotype

Skeletal abnormalities and impaired bone development

Human disease relevance

Skeletal disorders, osteoporosis

Model applications

Bone development and endocrine signaling models

Keywords:

GPCR, calcium homeostasis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Pth1r

conditional Knockout mouse

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