Rad18 conditional Knockout mouse

Target

Gene symbol :

Rad18

NCBI gene ID :

58186

Gene full name :

RAD18 E3 ubiquitin protein ligase

Synonym :

RNF159, HLTF

Protein function

Protein name :

RAD18

Ubiquitin ligase in DNA damage tolerance and post-replication repair

Expected phenotype

Genomic instability, hypersensitivity to DNA damage

Human disease relevance

Linked to cancer predisposition and genomic instability syndromes

Model applications

DNA repair and genomic stability models

Keywords:

E3 ligase, DNA repair, Replication

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Rad18

conditional Knockout mouse

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