Raf1 conditional Knockout mouse

Target

Gene symbol :

Raf1

NCBI gene ID :

110157

Gene full name :

Raf-1 proto-oncogene, serine threonine kinase

Synonym :

c-Raf, Raf-1

Protein function

Protein name :

RAF1 kinase

Serine threonine kinase regulating MAPK ERK signaling controlling cell proliferation, differentiation, and survival

Expected phenotype

Embryonic lethality, developmental defects, impaired cell signaling

Human disease relevance

Cancer, Noonan syndrome

Model applications

MAPK signaling and cancer models

Keywords:

protein kinase, MAPK signaling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Raf1

conditional Knockout mouse

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