Rbck1 conditional Knockout mouse

Target

Gene symbol :

Rbck1

NCBI gene ID :

24105

Gene full name :

RanBP-type and C3HC4-type zinc finger containing 1

Synonym :

HOIL-1, HOIL1

Protein function

Protein name :

HOIL-1 E3 ubiquitin ligase

Component of LUBAC complex regulating NF-kappaB signaling and immune responses

Expected phenotype

Impaired immune signaling and inflammation defects

Human disease relevance

Immunodeficiency, inflammatory disease

Model applications

Immune signaling and ubiquitination models

Keywords:

ubiquitin ligase, NF-kappaB

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Rbck1

conditional Knockout mouse

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