Rbl1 conditional Knockout mouse

Target

Gene symbol :

Rbl1

NCBI gene ID :

19650

Gene full name :

Retinoblastoma-like protein 1

Synonym :

p107, RBLP

Protein function

Protein name :

RBL1 (p107)

Regulates cell cycle by repressing E2F transcription factors during G1 phase

Expected phenotype

Cell cycle deregulation, developmental defects

Human disease relevance

Involved in cancer predisposition and cell proliferation control

Model applications

Cell cycle studies, cancer biology

Keywords:

Cell cycle, Tumor suppressor, E2F

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Rbl1

conditional Knockout mouse

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