Target

Gene symbol :  
Rc3h1
NCBI gene ID :  
381305
Gene full name :  
Ring finger and CCCH-type zinc finger domains 1
Synonym :  
Roquin-1

Protein function

Protein name :  
Roquin-1 ubiquitin ligase
Regulates mRNA stability and immune signaling pathways

Expected phenotype

Autoimmune phenotypes and immune dysregulation

Human disease relevance

Autoimmune disease

Model applications

Immune regulation and RNA stability models

Keywords:

ubiquitin ligase, immune regulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Rc3h1

conditional Knockout mouse

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