Rfwd2 conditional Knockout mouse

Target

Gene symbol :

Rfwd2

NCBI gene ID :

26374

Gene full name :

Ring finger and WD repeat domain 2

Synonym :

COP1, E3 ubiquitin ligase

Protein function

Protein name :

RFWD2 (COP1)

E3 ubiquitin ligase targeting p53 and other transcription factors.

Expected phenotype

Growth defects, tumor-related phenotypes

Human disease relevance

Involved in cancer and developmental regulation

Model applications

Tumor suppression, transcription control

Keywords:

COP1, Ubiquitin, p53

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Rfwd2

conditional Knockout mouse

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