Target

Gene symbol :  
Scnn1b
NCBI gene ID :  
20277
Gene full name :  
Sodium channel epithelial 1 beta subunit
Synonym :  
ENaC beta, Beta-ENaC

Protein function

Protein name :  
Epithelial sodium channel beta subunit
Component of epithelial sodium channel regulating sodium transport and fluid balance

Expected phenotype

Impaired sodium balance and epithelial transport defects

Human disease relevance

Liddle syndrome, hypertension

Model applications

Ion transport and kidney physiology models

Keywords:

ion channel, sodium transport

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Scnn1b

conditional Knockout mouse

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