Smad3 conditional Knockout mouse

Target

Gene symbol :

Smad3

NCBI gene ID :

17127

Gene full name :

SMAD family member 3

Synonym :

Madh3

Protein function

Protein name :

SMAD3

Signal transducer for TGF-β pathway, regulating gene transcription and fibrosis.

Expected phenotype

Reduced fibrosis, altered immune response

Human disease relevance

Implicated in fibrosis, cancer, and autoimmune disorders

Model applications

Fibrosis, TGF-β signaling, immune regulation

Keywords:

TGF-β, Fibrosis, Immune modulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Smad3

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe