Sqle conditional Knockout mouse

Target

Gene symbol :

Sqle

NCBI gene ID :

20775

Gene full name :

Squalene epoxidase

Synonym :

Squalene epoxidase

Protein function

Protein name :

SQLE

Catalyzes the first oxygenation in cholesterol biosynthesis

Expected phenotype

Altered sterol levels, growth defects

Human disease relevance

Target for cholesterol-lowering agents, overexpressed in cancer

Model applications

Metabolic and cholesterol metabolism models

Keywords:

Cholesterol biosynthesis, Metabolic regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Sqle

conditional Knockout mouse

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