Target

Gene symbol :  
Sun1
NCBI gene ID :  
77053
Gene full name :  
Sad1 and UNC84 domain containing 1
Synonym :  
Sad1, UNC84 domain containing 1

Protein function

Protein name :  
SUN1 nuclear envelope protein
Component of LINC complex linking nucleus to cytoskeleton

Expected phenotype

Defects in nuclear positioning and cell structure

Human disease relevance

Muscular dystrophy, nuclear envelope disorders

Model applications

Nuclear architecture and mechanotransduction models

Keywords:

nuclear envelope, cytoskeleton

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sun1

conditional Knockout mouse

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