Tgm1 conditional Knockout mouse

Target

Gene symbol :

Tgm1

NCBI gene ID :

21816

Gene full name :

Transglutaminase 1

Synonym :

TGase1, TG1

Protein function

Protein name :

Transglutaminase-1

Enzyme catalyzing protein crosslinking in epidermis, essential for skin barrier formation

Expected phenotype

Severe skin barrier defects and neonatal lethality

Human disease relevance

Ichthyosis

Model applications

Skin biology and barrier function models

Keywords:

transglutaminase, epidermis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tgm1

conditional Knockout mouse

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