Tigar conditional Knockout mouse

Target

Gene symbol :

Tigar

NCBI gene ID :

319801

Gene full name :

TP53-induced glycolysis regulatory phosphatase

Synonym :

C12orf5

Protein function

Protein name :

TP53-induced glycolysis and apoptosis regulator

Regulates glycolysis and oxidative stress in a p53-dependent manner

Expected phenotype

Altered glucose metabolism and increased oxidative damage in KO

Human disease relevance

Linked to cancer metabolism and oxidative stress regulation

Model applications

Model for cancer metabolism, p53 signaling, redox control

Keywords:

p53, Metabolism, Oxidative stress, Glycolysis, Cancer

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tigar

conditional Knockout mouse

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