Target

Gene symbol :  
Tnfrsf1b
NCBI gene ID :  
21938
Gene full name :  
Tumor necrosis factor receptor superfamily member 1b
Synonym :  
Tnfr2, p75, CD120b

Protein function

Protein name :  
TNF receptor 2
Binds TNF; promotes cell survival, immune regulation, and tissue repair

Expected phenotype

Altered immune regulation; impacts T-cell function, inflammation, and tissue regeneration

Human disease relevance

Autoimmune diseases, inflammatory disorders, cancer immunology

Model applications

Immunology models, inflammation, TNF signaling studies

Keywords:

TNF signaling, immune regulation, inflammation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Tnfrsf1b

conditional Knockout mouse

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