Trp53 conditional Knockout mouse

Target

Gene symbol :

Trp53

NCBI gene ID :

22059

Gene full name :

Transformation related protein 53

Synonym :

p53, Tp53

Protein function

Protein name :

Cellular tumor antigen p53

Tumor suppressor regulating cell cycle, apoptosis, and DNA damage response

Expected phenotype

High tumor incidence, genomic instability

Human disease relevance

Cancer, Li-Fraumeni syndrome

Model applications

Cancer biology and DNA damage models

Keywords:

tumor suppressor, DNA repair

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Trp53

conditional Knockout mouse

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