Tyk2 conditional Knockout mouse

Target

Gene symbol :

Tyk2

NCBI gene ID :

54721

Gene full name :

Tyrosine kinase 2

Synonym :

JTK, PSEM, NAK, SIMK3

Protein function

Protein name :

TYK2

Janus-family kinase in type I interferon and IL-12 signaling

Expected phenotype

Immune deficiencies, cytokine signaling defects

Human disease relevance

Linked to immunodeficiency and susceptibility to infection

Model applications

Immunity and infection-response models

Keywords:

Kinase, JAK-STAT, Immunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tyk2

conditional Knockout mouse

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