Target

Gene symbol :  
Usp44
NCBI gene ID :  
327799
Gene full name :  
Ubiquitin specific peptidase 44
Synonym :  

Protein function

Protein name :  
Ubiquitin carboxyl-terminal hydrolase 44
Deubiquitinase regulating mitotic spindle checkpoint

Expected phenotype

KO leads to chromosomal instability and cancer predisposition

Human disease relevance

Implicated in aneuploidy and tumorigenesis

Model applications

Used in cell cycle, mitosis, and cancer research

Keywords:

Ubiquitin, Mitosis, Deubiquitinase, Spindle checkpoint, Cancer

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Usp44

conditional Knockout mouse

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