Zbtb24 conditional Knockout mouse

Target

Gene symbol :

Zbtb24

NCBI gene ID :

268294

Gene full name :

Zinc finger and BTB domain containing 24

Synonym :

Cxxc13

Protein function

Protein name :

Zinc finger and BTB domain-containing protein 24

Transcriptional regulator involved in epigenetic control and DNA methylation

Expected phenotype

KO results in impaired hematopoiesis and developmental defects

Human disease relevance

Mutations cause ICF syndrome type 2

Model applications

Model for immunodeficiency and epigenetic regulation

Keywords:

Zinc finger, ICF syndrome, Epigenetics, DNA methylation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Zbtb24

conditional Knockout mouse

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