Zmiz1 conditional Knockout mouse

Target

Gene symbol :

Zmiz1

NCBI gene ID :

328365

Gene full name :

Zinc finger MIZ-type containing 1

Synonym :

Zimp10

Protein function

Protein name :

Zinc finger MIZ domain-containing protein 1

Transcriptional co-activator; interacts with Notch and androgen receptor

Expected phenotype

KO results in embryonic lethality and hematopoietic defects

Human disease relevance

Linked to autoimmune diseases and leukemia

Model applications

Model for transcriptional co-regulation and immunity

Keywords:

Notch signaling, Transcriptional coactivator, Hematopoiesis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Zmiz1

conditional Knockout mouse

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