CRISPR/Cas9-Based Mouse Model Development

Mouse Models

Since 2013, we have been heavily investing in CRISPR/Cas9-based mouse model development, and have designed a unique offer, combining our:

Expertise in model design
Rigorous quality controls for mouse models

With the advantages of gene editing technologies, such as:

Cost effectiveness
Short development time

^{Get supplemental information, a quote, and estimated timeframe to generate your mouse line.}

"We are applying CRISPR/Cas9 technology to create Knockouts and Knockins in outbred,
and more fragile inbred genetic backgrounds such as C57BL/6."

You will benefit from:

Three independent genetically modified lines

Freedom to operate thanks to our unique IP portfolio, including a license from Broad Institute (MIT)

Off-target measurement

Short development time

"We were highly impressed by the expert manner in which genOway’s scientists managed what I felt to be a rather..." > read full testimonial

Prof. Simon C. ROBSON
Director at Beth Israel Deaconess Medical Center

"We were highly impressed by the expert manner in which genOway’s scientists managed what I felt to be a rather difficult mutant mouse project and achieved success within their proposed timelines. The project leader deserves a lot of praise for his expertise and preparation of the detailed, clear and concise reports that arrived at all the expected times. Their collaboration with Charles River regarding the mouse line transfer to our animal facility in Boston was an additional advantage. I can highly recommend their services."

Prof. Simon C. ROBSON
Director at Beth Israel Deaconess Medical Center

Publications

Chin C et al.
Cell Rep Med. 2023 Feb 9

Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis
Helou DG et al.
J Allergy Clin Immunol. 2023 Feb

Human PD-1 agonist treatment alleviates neutrophilic asthma by reprogramming T cells

CRISPR/Cas9-Based Mouse Model Development

Further reading