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Applications of the genO‑hTNF-α mouse model
Useful applications for researchers working on different biomedical fields, such as inflammation and autoimmunity:
- Assess the efficacy of TNF-α-targeting therapeutics
- Investigate the mode of action (MoA) of various compounds and understand their therapeutic potential
Features
- Physiological regulation and expression pattern of TNF-α
- Conservation of the TNF-α downstream signaling
- No expression of murine TNF-α
- Fully functional mouse immune system
Clients
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