Target

Gene symbol :  
Adh5
NCBI gene ID :  
11532
Gene full name :  
Alcohol dehydrogenase 5
Synonym :  
Gsnor, GSH formaldehyde dehydrogenase

Protein function

Protein name :  
ADH5
Detoxifies formaldehyde and regulates nitric oxide levels through S-nitrosoglutathione reduction.

Expected phenotype

Altered NO metabolism, formaldehyde sensitivity

Human disease relevance

Linked to asthma, cancer, S-nitrosylation regulation

Model applications

Nitric oxide biology, detoxification pathways

Keywords:

Formaldehyde, NO, Redox balance

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Adh5

conditional Knockout mouse

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