Bmpr2 conditional Knockout mouse

Target

Gene symbol :

Bmpr2

NCBI gene ID :

12168

Gene full name :

Bone morphogenetic protein receptor type II

Synonym :

BMPRII, Alk3b

Protein function

Protein name :

BMPR2

Serine/threonine kinase receptor in BMP signaling; regulates vascular and bone development.

Expected phenotype

Vascular remodeling defects, altered bone growth

Human disease relevance

Associated with pulmonary arterial hypertension (PAH)

Model applications

Vascular disease models, bone signaling

Keywords:

BMP signaling, PAH, TGF-beta pathway

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Bmpr2

conditional Knockout mouse

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