C8b conditional Knockout mouse

Target

Gene symbol :

C8b

NCBI gene ID :

110382

Gene full name :

Complement component 8, beta polypeptide

Synonym :

Complement component 8 beta chain

Protein function

Protein name :

C8 beta chain

Component of complement membrane attack complex (MAC); essential for innate immunity

Expected phenotype

Knockouts result in impaired MAC formation and immune defense

Human disease relevance

Deficiency linked to increased susceptibility to Neisseria infections

Model applications

Studied in innate immunity and complement system

Keywords:

Complement, MAC, Innate immunity, C8 complex

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

C8b

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe