Target

Gene symbol :  
Cenpe
NCBI gene ID :  
229841
Gene full name :  
Centromere protein E
Synonym :  

Protein function

Protein name :  
CENP-E
Kinesin-like motor protein required for chromosome alignment during mitosis

Expected phenotype

KO causes mitotic arrest and embryonic lethality

Human disease relevance

Associated with microcephaly and mosaic variegated aneuploidy

Model applications

Studied in mitosis, chromosome segregation, and developmental disorders

Keywords:

Mitosis, Chromosome alignment, CENP, Cell cycle

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cenpe

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe