Cep164 conditional Knockout mouse

Target

Gene symbol :

Cep164

NCBI gene ID :

214552

Gene full name :

Centrosomal protein 164

Synonym :

KIAA1052

Protein function

Protein name :

Centrosomal protein of 164 kDa

Required for primary cilia formation; key in DNA damage response and ciliogenesis

Expected phenotype

KO leads to impaired ciliogenesis and developmental abnormalities

Human disease relevance

Mutations cause nephronophthisis and other ciliopathies

Model applications

Used in cilia biology and kidney disease models

Keywords:

Ciliogenesis, Centrosome, DNA damage, Nephronophthisis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cep164

conditional Knockout mouse

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