Target

Gene symbol :  
Cfh
NCBI gene ID :  
12628
Gene full name :  
Complement factor H
Synonym :  
Complement H factor

Protein function

Protein name :  
CFH
Regulates complement activation to prevent host cell damage.

Expected phenotype

Complement dysregulation, inflammation

Human disease relevance

Associated with AMD and atypical HUS

Model applications

Complement regulation, immune response

Keywords:

Complement, HUS, AMD

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cfh

conditional Knockout mouse

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