Cfi conditional Knockout mouse

Target

Gene symbol :

Cfi

NCBI gene ID :

12630

Gene full name :

Complement factor I

Synonym :

Complement I factor

Protein function

Protein name :

CFI

Cleaves and inactivates C3b and C4b in the complement pathway.

Expected phenotype

Impaired complement control, inflammation

Human disease relevance

Linked to age-related macular degeneration, HUS

Model applications

Immune homeostasis, complement disorders

Keywords:

Complement, Protease, Immune regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cfi

conditional Knockout mouse

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