Coq2 conditional Knockout mouse

Target

Gene symbol :

Coq2

NCBI gene ID :

71883

Gene full name :

Coenzyme Q2, polyprenyltransferase

Synonym :

ADCK4

Protein function

Protein name :

4-hydroxybenzoate polyprenyltransferase, mitochondrial

Catalyzes early steps of Coenzyme Q biosynthesis in mitochondria

Expected phenotype

Knockouts show CoQ deficiency, renal failure, and early lethality

Human disease relevance

Linked to CoQ10 deficiency and nephrotic syndrome

Model applications

Used in studies of mitochondrial bioenergetics and kidney disease

Keywords:

Mitochondria, Coenzyme Q, Nephrotic syndrome, Ubiquinone

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Coq2

conditional Knockout mouse

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