Target

Gene symbol :  
Cttn
NCBI gene ID :  
13043
Gene full name :  
Cortactin
Synonym :  
Cortactin, EMS1

Protein function

Protein name :  
CTTN
Actin-binding scaffold protein involved in cytoskeletal dynamics, endocytosis, and migration.

Expected phenotype

Impaired cell motility and actin reorganization

Human disease relevance

Overexpressed in metastatic cancers

Model applications

Cancer cell invasion, cytoskeletal regulation

Keywords:

Actin, Migration, Invasion

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
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Cttn

conditional Knockout mouse

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