Cyfip1 conditional Knockout mouse

Target

Gene symbol :

Cyfip1

NCBI gene ID :

20430

Gene full name :

Cytoplasmic FMR1-interacting protein 1

Synonym :

CYFIP1, SYWNR, P400

Protein function

Protein name :

CYFIP1

Regulates actin dynamics via WAVE complex and translation repression

Expected phenotype

Neurological defects, altered synaptic morphology

Human disease relevance

Linked to autism spectrum disorders and intellectual disability

Model applications

Synapse biology, neurodevelopment models

Keywords:

Actin regulation, Synaptic development, Autism

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cyfip1

conditional Knockout mouse

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