Dicer1 conditional Knockout mouse

Target

Gene symbol :

Dicer1

NCBI gene ID :

192119

Gene full name :

Dicer 1, ribonuclease type III

Synonym :

Dicer

Protein function

Protein name :

Endoribonuclease Dicer

Key enzyme in microRNA and siRNA processing; essential for RNA silencing

Expected phenotype

Knockouts are embryonically lethal; tissue-specific KOs cause various defects

Human disease relevance

Mutations linked to DICER1 syndrome and cancer predisposition

Model applications

Widely used in RNAi, miRNA biogenesis, and cancer research

Keywords:

RNAi, microRNA, Gene silencing, Cancer, Development

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Dicer1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe