Dnase2b conditional Knockout mouse

Target

Gene symbol :

Dnase2b

NCBI gene ID :

56629

Gene full name :

Deoxyribonuclease II beta

Synonym :

DLAD, DNase II-like acid DNase beta

Protein function

Protein name :

DNAse II-like acid DNase beta

Degrades DNA during cell death and terminal differentiation in lens

Expected phenotype

Lens fiber degeneration, eye malformations

Human disease relevance

Cataracts and ocular development models

Model applications

Lens development, apoptosis, DNase

Keywords:

Eye development, DNase, Apoptosis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Dnase2b

conditional Knockout mouse

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