Elmod2 conditional Knockout mouse

Target

Gene symbol :

Elmod2

NCBI gene ID :

244548

Gene full name :

ELMO domain containing 2

Synonym :

—

Protein function

Protein name :

Engulfment and cell motility domain-containing protein 2

Acts as GTPase-activating protein (GAP) for ARF family GTPases

Expected phenotype

KO affects mitochondrial morphology and antiviral response

Human disease relevance

Associated with idiopathic pulmonary fibrosis in humans

Model applications

Studied in mitochondrial dynamics and innate immunity

Keywords:

ARF GAP, Mitochondria, Innate immunity, Cell motility

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Elmod2

conditional Knockout mouse

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