Target

Gene symbol :  
Entpd1
NCBI gene ID :  
12495
Gene full name :  
Ectonucleoside triphosphate diphosphohydrolase 1
Synonym :  
Cd39

Protein function

Protein name :  
CD39
Degrades extracellular ATP and ADP to AMP; regulates purinergic signaling and inflammation.

Expected phenotype

Altered inflammation and immune regulation

Human disease relevance

Target in immunotherapy and thrombosis

Model applications

Immunosuppression, Treg function, inflammation

Keywords:

ATP metabolism, Tregs, Immunotherapy

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Entpd1

conditional Knockout mouse

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