Entpd1 conditional Knockout mouse

Target

Gene symbol :

Entpd1

NCBI gene ID :

12495

Gene full name :

Ectonucleoside triphosphate diphosphohydrolase 1

Synonym :

Cd39

Protein function

Protein name :

CD39

Degrades extracellular ATP and ADP to AMP; regulates purinergic signaling and inflammation.

Expected phenotype

Altered inflammation and immune regulation

Human disease relevance

Target in immunotherapy and thrombosis

Model applications

Immunosuppression, Treg function, inflammation

Keywords:

ATP metabolism, Tregs, Immunotherapy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Entpd1

conditional Knockout mouse

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