Fbxl21 conditional Knockout mouse

Target

Gene symbol :

Fbxl21

NCBI gene ID :

213311

Gene full name :

F-box and leucine-rich repeat protein 21

Synonym :

Fbl11

Protein function

Protein name :

F-box/LRR-repeat protein 21

Part of SCF E3 ubiquitin ligase complex; regulates circadian clock proteins

Expected phenotype

Disruption alters circadian period and PER protein degradation

Human disease relevance

Linked to circadian rhythm disorders

Model applications

Used in circadian biology and proteostasis studies

Keywords:

Ubiquitination, Circadian rhythm, SCF complex, PER degradation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Fbxl21

conditional Knockout mouse

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