Target

Gene symbol :  
Gabarapl2
NCBI gene ID :  
93739
Gene full name :  
GABA type A receptor associated protein–like 2
Synonym :  
0610012F20Rik, 2900019O08Rik, GATE‑16, Gef2

Protein function

Protein name :  
GATE‑16 (GABARAPL2)
ATG8 family autophagy protein involved in autophagosome formation and ER turnover

Expected phenotype

Knockouts show autophagy defects; impacts ER-phagy and stress responses

Human disease relevance

Linked to neurodegeneration and proteostasis disorders

Model applications

Studied in autophagy, neurobiology, and ER homeostasis

Keywords:

Autophagy, ATG8, ER turnover, Proteostasis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Gabarapl2

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe