Gfi1b conditional Knockout mouse

Target

Gene symbol :

Gfi1b

NCBI gene ID :

14582

Gene full name :

Growth factor independent 1B transcription repressor

Synonym :

Gfi-1B

Protein function

Protein name :

GFI1B

Zinc finger transcription repressor essential for erythropoiesis and platelet development.

Expected phenotype

Anemia, thrombocytopenia

Human disease relevance

Implicated in myelodysplastic syndromes and leukemia

Model applications

Hematopoiesis, blood lineage models

Keywords:

Transcription factor, Erythroid, Platelet

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gfi1b

conditional Knockout mouse

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