Target

Gene symbol :  
Gfi1b
NCBI gene ID :  
14582
Gene full name :  
Growth factor independent 1B transcription repressor
Synonym :  
Gfi-1B

Protein function

Protein name :  
GFI1B
Zinc finger transcription repressor essential for erythropoiesis and platelet development.

Expected phenotype

Anemia, thrombocytopenia

Human disease relevance

Implicated in myelodysplastic syndromes and leukemia

Model applications

Hematopoiesis, blood lineage models

Keywords:

Transcription factor, Erythroid, Platelet

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Gfi1b

conditional Knockout mouse

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