Target

Gene symbol :  
Jmjd1c
NCBI gene ID :  
108829
Gene full name :  
Jumonji domain containing 1C
Synonym :  
KDM3C, TRIP8

Protein function

Protein name :  
Histone demethylase JMJDC1
Histone lysine demethylase involved in transcription regulation and germ cell development

Expected phenotype

Knockouts affect fertility, hematopoiesis, and metabolism

Human disease relevance

Associated with cancer, neurodevelopmental, and metabolic disorders

Model applications

Studied in epigenetics, spermatogenesis, and cancer

Keywords:

Histone demethylation, Epigenetics, Fertility, KDM family

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Jmjd1c

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe