Target

Gene symbol :  
Kng2
NCBI gene ID :  
385643
Gene full name :  
Kininogen 2
Synonym :  
Tkininogen, Kng-2

Protein function

Protein name :  
Kininogen-2
Precursor of kinin peptides involved in vasodilation and inflammation

Expected phenotype

Reduced inflammation response in deficient models

Human disease relevance

Altered kinin pathways associated with cardiovascular and inflammatory diseases

Model applications

Model for inflammation, blood pressure regulation, and pain

Keywords:

Kallikrein-kinin, Inflammation, Vasodilation, Cardiovascular

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Kng2

conditional Knockout mouse

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