Mfn2 conditional Knockout mouse

Target

Gene symbol :

Mfn2

NCBI gene ID :

170731

Gene full name :

Mitofusin 2

Synonym :

Marf, HSG

Protein function

Protein name :

Mitofusin-2

Mediates mitochondrial fusion and ER-mitochondria tethering

Expected phenotype

Knockouts result in mitochondrial fragmentation and neuropathy-like phenotypes

Human disease relevance

Mutations cause Charcot-Marie-Tooth disease type 2A

Model applications

Used in mitochondrial dynamics and neurodegeneration studies

Keywords:

Mitochondrial fusion, Mitophagy, Charcot-Marie-Tooth, ER-mito contacts

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mfn2

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe