Mrap2 conditional Knockout mouse

Target

Gene symbol :

Mrap2

NCBI gene ID :

244958

Gene full name :

Melanocortin 2 receptor accessory protein 2

Synonym :

—

Protein function

Protein name :

Melanocortin 2 receptor accessory protein 2

Regulates melanocortin receptor trafficking and signaling

Expected phenotype

KO leads to hyperphagia and obesity

Human disease relevance

Variants associated with obesity in humans

Model applications

Studied in energy balance, obesity, and neuroendocrine signaling

Keywords:

Obesity, GPCR regulation, Energy homeostasis, MC4R

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mrap2

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe